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Ferroptosis-inducing factors can directly or indirectly affect glutathione peroxidase through different pathways, resulting in a decrease in antioxidant capacity and accumulation of lipid reactive oxygen species (ROS) in cells, ultimately leading to oxidative cell death

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Caption: Plasma GHK-Cu concentrations decline by more than 60 percent between ages 20 and 60, a trajectory that tracks closely with the loss of regenerative capacity