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Dihexa for Coeliac & Gluten Brain Fog The Yelland 2017 gluten-induced cognitive impairment review, the Lichtwark 2014 mucosal-healing cognition data, the Addolorato 2004 SPECT finding of reversible cerebral hypoperfusion in 73% of untreated coeliac patients, the Sheffield gluten-neurology / transglutaminase-6 tradition (Hadjivassiliou), NICE NG20, the malabsorption drivers, and Coeliac UKs ~1 in 100 / ~500,000-undiagnosed figures

Instead, they were derived from large observational cohorts, retrospective comparative analyses, and pooled real-world datasets

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The era in which compounders could market these products with aggressive, consumer-facing advertising and minimal regulatory scrutiny appears to be closing