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What are the risks of adding an unproven compound to a GLP-1 regimen

Subjects performed the oral l-carnitine challenge test by consuming 250 mg of synthetic d 3 (methyl)-l-carnitine within a capsule (Vegicap, Catalent), followed by serial venous plasma draws collected in EDTA vacutainer tubes for d 3 -l-carnitine metabolite quantification

However, a phase 4 study conducted over a long period did not discover an elevated risk of bleeding associated with glutathione use

39,40 Enhancing the Adoption of These Agents Although numerous clinical trials have shown the significant benefits of cardiovascular and renal protection for individuals with diabetes and CKD, adoption of GLP-1RA in clinical practice remains low