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Product Specifications: Composition: Water for Injection, USP with 0.9% (9 mg/mL) Benzyl Alcohol, NF (bacteriostatic preservative) Volume: 30mL per sterile vial Container Type: Type I borosilicate glass vial with sterile rubber closure and aluminum overseal pH: 4.5 7.0 (per USP monograph) Osmolality: Hypotonic (approximately 0 mOsm/kg) Sterility Assurance Level: 10 (terminal steam sterilization) Bacterial Endotoxin: Bacterial Endotoxins Test Particulate Matter: Complies with USP Particulate Matter specifications FOR RESEARCH USE ONLY

(2) Sores typically heal without scarring, although scarring is possible with a major lesion

Itaconate promotes tumor growth via oxidative phosphorylation-driven ROS generation in peritoneal tissue-resident macrophages and concomitant ROS-mediated mitogen-activated protein kinases (MAPKs) activation in tumor cells (79)