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The fact that a peptide isolated from gastric juices seems to have such a profound impact on the brain bolsters this claim

For example, lactoferrin in horse semen was closely bound to SOD3, and the protein complex was selectively bound to non-viable sperm, which might be labeled by phagocytosis of neutrophils to identify live sperm and dead sperm [92]

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In its active form, the peptide binds divalent copper ions (Cu), with the histidine residue serving as the primary coordination site