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Other indications include malabsorption disorders (such as Crohn's disease or coeliac disease), following gastric surgery, strict vegan diets without supplementation, and certain medications that interfere with B12 absorption
That said, the components, the vitamins themselves, are well studied, and compounders must adhere to strict quality standards
If you are reducing from 10 mg to 7.5 mg to 5 mg over successive months, your ml draw decreases at each step
Studies have shown that supplementing cobalamin in deficient cats experiencing gastrointestinal disease, like vomiting and diarrhea, has led to a significant improvement in GI signs, as well as weight gain
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