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But the physiological rationale is sound: slower weight loss, matched with structured resistance training and adequate protein, should produce a better body composition outcome than the maximal-dose, rapid-loss approach the STEP trials optimized for

[25] Instead, the guidelines emphasize comprehensive cardiometabolic risk reduction through improved glycemic control, weight management, blood pressure control, and lipid management

Afterwards, 1 ml was taken from each phase and added to the respective phases collected during the previous extraction