Importantly, BPC-157 is not FDA-approved and is legally prohibited for sale as a drug, dietary supplement, or food additive in the US
What they found (summary): MC1R: melanogenesis, pigmentation, anti-inflammation MC2R: ACTH receptor in the adrenals (Melanotan II does not act) MC3R: energy, cardiovascular function, anti-inflammation MC4R: appetite (central control), sexual function, autonomic regulation MC5R: exocrine glands (sebaceous, lacrimal, salivary) Mutations in MC4R are the most common monogenic cause of obesity in humans Why it matters: Cones review article is the reference article for all of melanocortin pharmacology
Individuals with confirmed copper allergy, typically identified through jewelry reactions or patch testing, should avoid copper peptides
Dan Med Bull 1998;45:459-79