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Wogonoside can significantly reduce airway inflammation and excessive mucus production while enhancing airway remodeling by inhibiting the activation of NF-B and STAT6 in lung tissue and bronchial epithelial cells, as well as decreasing Th2-related cytokines (IL-4, IL-5, IL-13) in lung tissue and serum IgE levels (315)

The evidence base, however, varies dramatically by peptide

In this study, the team chose to investigate the role of a neurotransmitter called vasoactive intestinal peptide, as it has previously been linked to anti-inflammatory effects, meaning it could have a protective effect on disc tissue

Metabolic improvement after gastric bypass correlates with changes in IGF-regulatory proteins stanniocalcin-2 and IGFBP-4