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Solar Lentigines (Sun Spots / Age Spots) Developed from years of accumulated UV exposure Common in adults over 30, even on medium or darker skin tones Do NOT fade in winter, they stay year-round Sit deeper in the skin layers Require professional treatments such as Pico Laser or Q-Switched Nd: YAG for effective removal If you have been using brightening creams for freckles for months with little improvement, you likely have solar lentigines, not ephelides

In the semaglutide + lifestyle counseling group, changes were +0.03 ng/mL for CTX (95% CI: 0.03 to 0.09) and +0.63 ng/mL for P1NP (95% CI: 5.48 to 6.73)