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Two further limitations apply directly to KLOW

In a retrospective study wherein BMI was used as a proxy for adiposity (median age 40 yr, range 2077 yr, median BMI 26 kg/m2, range 18.349.8 kg/m2), total and pulsatile 24 hour GH secretion were both negatively associated with BMI, and GH secretion was higher in women than men below 50 years of age, likely due to the influence of estradiol levels on IGF-1 levels (22) (Figures 3,4)

(2024) Protocol for the in vitro reconstruction of site-specifically phosphorylated RNA Pol II to identify the recruitment of novel transcription regulators

10.1016/j.omtn.2020.03.003 22 Bertoncini-SilvaC.VladA.RicciarelliR.Giacomo FassiniP.SuenV