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At the cellular level, studies suggest GLP-1 therapy may influence biological processes relevant to aging

Pen prescribing tips If patients receive a starter kit that includes four 0.25 mg Wegovy pens, check the samples given box in their electronic health record Write prescription for 0.5 mg For those who do not receive a sample, write a prescription for 0.25 mg Check to make sure the dispense quantity unit of measure is mL only Always choose semaglutide (Wegovy ) for the intended indication when searching the product database When titrating patients up to 7.2 mg, you may need to select Wegovy HD For patients who tolerate the 2.4 mg dosage for at least 4 weeks and additional weight reduction is clinically indicated, the dosage may be increased to a maximum dosage of 7.2 mg subcutaneously once weekly Consider treatment response and tolerability when selecting the maintenance dosage Consider, when appropriate, writing a physical script for your patients to fill at their pharmacy of choice Encourage your patients to check in throughout their dose-escalation schedule to assess progress and tolerability After your patients reach their maintenance dose, you can consider a 3-month Rx Important to Remember: A new prescription is required for each dose strength Integrated needle means no separate Rx or co-pay A prior authorization may be required if patient is using commercial insurance Example Rx for the 0.25 mg starting dose: How to prescribe the once-daily Wegovy pill 1 * The Wegovy pill comes in 4 different strengths

It develops when there is excess fat in liver cells due to too much fatty acid uptake in the liver, excess synthesis of fat in the liver, and not enough fat exported out of the liver

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