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Recombinant human GLP-1 beinaglutide regulates lipid metabolism of adipose tissues in diet-induced obese mice

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Lipopolysaccharide (LPS) from gram-negative bacteria translocates into systemic circulation, triggering NF-B signalling and a cytokine storm (TNF-, IL-1, IL-6, IL-8)

Hao Y, Samuels Y, Li Q, Krokowski D, Guan BJ, Wang C, Jin Z, Dong B, Cao B, Feng X, Xiang M, Xu C, Fink S, Meropol NJ, Xu Y, Conlon RA, Markowitz S, Kinzler KW, Velculescu VE, Brunengraber H, Willis JE, Laframboise T, Hatzoglou M, Zhang GF, Vogelstein B, Wang Z (2016) Oncogenic PIK3CA mutations reprogram glutamine metabolism in colorectal cancer