Pallauf K, Chin D, Gnther I, Birringer M, Lersen K, Schulthei G, Vieten S, Krau J, Bracher F, Danylec N, Soukup ST (2019) Resveratrol, lunularin and dihydroresveratrol do not act as caloric restriction mimetics when administered intraperitoneally in mice
Change history 03 October 2017 A correction has been published and is appended to both the HTML and PDF versions of this paper
As expected, the GSH levels were reduced by 100 M of hydrogen peroxide but enhancing network activity with blockers of GABA A receptors (bicuculine) and KCNA channels (4-AP) attenuated this effect
These findings support the notion that, similar to the development of peripheral opioid receptor antagonists, developing therapeutic targeting specific brain regions is one of several avenues that warrant exploration for patients unresponsive to current therapies