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As CGN cannot be hydrolyzed to PGN in vivo , concerns over the use of CGN as a food additive are unfounded, particularly since current studies support the lack of oncogenic and tumorigenic activity of CGN in humans

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Animals were not used for multiple experiments as two of the three experiments were non-survival (due to the blood collection following DMRS and the urethane anesthesia used for fMRI) and incompatible (DMRS and PET both required labeled glucose injection, the DMRS and fMRI signals may interfere with each other, and fMRI required different anesthesia than the other two experiments)

Instead, look at a weekly trend over several weeks