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doi: 10.3389/fphar.2011.00068

Increased insulin-like growth factor-1 activity has been reported in cases of polycystic kidney disease, while IGF-1 resistance where the body produces enough of this polypeptide but is unable to metabolize or use it is seen in many cases of chronic kidney failure

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Parameters to monitor BP and pulse Peripheral edema -blockers See Table 12-12 for a list of -blockers, their usual dosage range, and adverse effects associated with these medications