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Additionally, semaglutide often reduces overall food intake, meaning less fiber and bulk reach your intestines, further contributing to harder, less frequent stools
Semaglutide is indicated for chronic weight management in adults with a BMI of 27 kg/m or greater who have at least one weight-related comorbidity, such as type 2 diabetes or hypertension, or in adults with a BMI of at least 30 kg/m
Trp metabolism in the intestine, as well as exogenous IAA and IPA, enhances M2 macrophages and bolsters the massive diffusion of IL-10 from the intestinal lamina propria to the bone marrow, thereby significantly promoting osteogenesis (70)
61 , e202115764 (2022)
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