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G.BresE.VrtesiA.FrankZ.PasicsI.EndresJ.et al (2011)

Resistance mechanisms and adaptation to therapeutic stress CSCs possess a diverse array of intrinsic and extrinsic resistance mechanisms that enable them to withstand chemotherapy, radiation, and targeted therapies

The authors found dose-dependent GH release without concurrent rises in prolactin, ACTH, or cortisol at any dose tested

These results may suggest that GLP-1R agonists may alleviate the bloodbrain barrier breakdown induced by inflammatory factors, which is sometimes observed in depression [65]