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10.1371/journal.pone.0034263 149 SkopelitouK.MuletaA
IB and IP products and WCL derived from HEK293 cells transfected with indicated constructs
Future research should develop longitudinal datasets to enable analysis of weight loss and side effects in the context of dosage escalations, while exploring genetic factors, which could then inform how genetics might be leveraged in clinical decision-making at treatment initiation and beyond
Conclusions Evidence accrued so far suggest that GLP-1RA could exert a modest renal benefit alongside CV protection, justifying its place as second-line drug in patients with T2D and CKD not achieving glycemic control with SGLT-2i and metformin according to KDIGO guidelines [87]
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