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Upper gastrointestinal series suggested: The stomach was folded, with the pylorus and gastric fundus entering the thoracic cavity, and there was obstruction at the gastric outlet (Figure 1B)

Diagnosis often occurs incidentally, as fatty liver disease rarely causes symptoms in early stages

NMR validation of 1907 interactions and circular dichroism To validate the binding mode of 1907 and map its interactions with the FAT domain, we performed heteronuclear single quantum coherence-nuclear magnetic resonance (HSQC-NMR) chemical shift perturbation (CSP) studies with 15 N labeled recombinant FAT protein and titrating amounts of 1907 from 100 nM to 200 M (Fig