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Most of what we know comes from our understanding of how each substance works individually and from anecdotal reports

The Safety Concerns With Unregulated Weight Loss Supplements Dietary supplements operate under looser FDA oversight than pharmaceutical drugs, meaning manufacturers do not need to prove safety or efficacy before marketing

And the medications in question are pretty darned important were talking about antidepressants, antiseizure drugs, blood thinners (anticoagulants) and statins