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Abstract Psoriasis is a chronic, immune-mediated disorder with cutaneous and systemic manifestations and substantial negative effects on patient quality of life

Prolonged kappa opioid receptor phosphorylation mediated by G-protein receptor kinase underlies sustained analgesic tolerance

Neurobiological Research A growing body of published research has examined this compounds interactions with dopaminergic, serotonergic, and GABAergic neurotransmitter systems in animal research models