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We may conclude that the bone mass alteration in patients with AN is dual: an increase of resorption and a decrease of bone formation

Therefore, they share the same half-life of approximately seven days

The nanoparticle, composed of an octameric ribonucleoprotein scaffold and endosomolytic peptides, was functionalized with targeting ligands and siRNAs, yielding a slightly negative charge that improved tumor penetration and biocompatibility

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