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doi: 10.1371/journal.pone.0056660

NAPQI, characterized by its reactive quinone imine group, is prone to redox reactions and may lead to the generation of reactive oxygen species (ROS)

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First, while outsourcing facilities may argue that supplying to 503A pharmacies mitigates exposure by shifting prescription-level responsibility, FDA has not explicitly sanctioned 503B-to-503A fulfillment for drugs no longer on shortage