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A registered dietitian understands how to balance macros for weight-loss patients on medication optimizing protein-to-calorie ratios, including micronutrient-rich ingredients, and sizing portions for reduced appetite

By targeting multiple pathways simultaneously, these next-generation drugs may further enhance brain health, improve vascular integrity and potentially provide stronger protection against conditions like cognitive impairment, vascular dementia and ADRD, she wrote

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This improvement is achieved by activating the Nrf2/HO-1 antioxidant pathway, inhibiting the NF-B-mediated inflammatory response, and blocking the TGF-/Smad3 fibrotic pathway as well as the Ripk1/Ripk3/Mlkl necroptosis pathway [231]