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In a subsequent prospective cohort, liraglutide not only improved metabolic parameters but also demonstrated immunomodulatory effects, with a significant reduction in circulating T-cell populations, particularly T cells, which are known to play a key role in PsO pathogenesis by producing IL17 and IL22 (26)

doi: 10.1155/2021/3361309 71 DaniilopoulouIVlachouELambrouGINtikoudiADokoutsidouEFasoiGet al

The central challenge lies in precisely determining whether to inhibit or activate autophagic pathways, a decision that depends on the specific molecular context, including the driver mutation and the resistance mechanism at play

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