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Rybelsus addresses this by combining oral semaglutide with an absorption enhancer, sodium N-(8-[2-hydroxybenzoyl] amino) caprylate, or SNAC, that enables a small fraction of the molecule to reach systemic circulation

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Because we also found that treatment with MT still decreases cell proliferation of TRIP13-KO cells, combining MT with the TRIP13 inhibitor DCZ0415 would likely have an additive anti-proliferative therapeutic effect in the treatment of NSCLC