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The peptide was developed through research into hypothalamic-pituitary regulatory peptides and represents one of the smallest bioregulatory peptide fragments described in the scientific literature

Degterev A, Huang Z, Boyce M, et al Chemical inhibitor of nonapoptotic cell death with therapeutic potential for ischemic brain injury

Adipose Tissue and Lipid Metabolism Research The primary and most extensively published research application of this GH fragment is the investigation of adipose tissue biology and lipid metabolism pathways

There is a theoretical concern, supported by some biological evidence, that elevated IGF-1 activity in a patient with occult or a history of certain hormone-sensitive cancers could be problematic