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En maratonistas o ciclistas de ruta que realizan de forma sistemtica esfuerzos prolongados e intensos, cercanos e incluso por encima del 2 umbral, la suplementacin oral con L-carnitina por ms de 14 das, ha mostrado ser efectiva para mantener e incluso incrementar los niveles de carnitina muscular, evitando su reduccin significativa (respecto a un grupo control) luego de varios das de esfuerzos intensivos como los que se producen durante un Tour de Francia o una vuelta a Espaa (Cerretelli & Marconi 1990, Di Pasquale 1997)