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CJC-1295 has several modifications for improved pharmacokinetics, including the substitution of four amino acids in the original 29 amino acid chain, which improves the peptides stability and effectiveness [4, 5, 6]: At the second position, L-alanine is replaced with D-alanine, heightening resistance to the enzyme dipeptidyl peptidase-4 (DPP-4), which plays a crucial role in deactivating many peptide-based medications

Impact of Branched Chain Amino Acid on Muscle Mass, Muscle Strength, Physical Performance, Combined Survival, and Maintenance of Liver Function Changes in Laboratory and Prognostic Markers on Sarcopenic Patients With Liver Cirrhosis (BCAAS Study): A Randomized Clinical Trial