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First identified in human plasma in the 1970s, this small tripeptide glycyl-L-histidyl-L-lysine, bound to a copper ion has become one of the most extensively referenced compounds in dermal and wound-healing research literature, largely because its copper-binding structure gives it a distinct mechanism from most other peptide sciences on the market

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doi: 10.1007/s00198-011-1868-7

In controlled laboratory research environments, GHK-Cu is widely studied for its role in peptide-mediated signaling, copper-dependent molecular regulation, and cellular communication pathways