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[6] A second study by Ionescu and Frohman gave a single injection to healthy men and showed that GH secretion rose driven mostly by a marked increase in trough GH while preserving the normal pulsatile pattern, with a corresponding rise in IGF-1

After 3 weeks, my jawline is so much more defined

However, the magnitude of effect is considerably smaller than that achieved with pharmaceutical GLP-1 receptor agonists