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Funding This paper was supported by San Matteo Hospital Foundation, Internal Medicine research fundings, PRIN2017. Publishers note All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

The same polymorphism was subsequently demonstrated to have a significantly lower incidence in patients who developed hepatotoxicity from unintentional paracetamol overdose when compared to liver failure from other causes [32]