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GLP-1 and GIP receptor agonists have a low intrinsic risk of causing hypoglycaemia when used alone, because their insulin-stimulating effects are glucose-dependent

The advantages of GLP-1 agonists include substantial clinical trial data supporting their efficacy and safety, FDA approval for weight management in certain populations, proven results with many users losing 15-20% or more of body weight, and effects on appetite that make caloric restriction feel natural

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Prices in those settings often are not covered by insurance because the visit is categorized as elective or cosmetic wellness rather than medical care