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This hypothesis aims to identify potential therapeutic targets for OCSCs

For instance, in a randomized, placebo-controlled trial in healthy adults, subcutaneous CJC-1295 injections produced sustained, dose-dependent increases in GH (two to 10 times) and IGF-1 (1.5 to three times) levels over several days, demonstrating prolonged GH axis stimulation without serious adverse effects, a hormonal milieu associated with anabolic and metabolic effects

After removing duplication using Endnote X8.0.1., 93 abstracts were evaluated, and 34 articles were suitable for full-text screening