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Technology Comparison: Metabolomics Platforms for MoA Research Instrumentation Sample Requirements Biological replicates: minimum 6 per group recommended for untargeted metabolomics to achieve adequate statistical power for differential feature detection

It has been demonstrated that cinnamaldehyde and cinnamon treatment leads to downregulation of the NF-B pathway and reduces the levels of proinflammatory cytokines in diseases such as T2D and atherosclerosis in ApoE / mice [124, 125]

The cumulative, sustained-release mechanism means gaps in dosing can reduce effectiveness

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