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The Loss of Exclusivity (LOE) of semaglutide in China, Brazil, Canada and India in 2026 will result in the availability of cheaper generics in these countries (and possibly neighbouring countries via parallel import)

To view a copy of this license, visit About this article Cite this article Melson, E., Ashraf, U., Papamargaritis, D

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Key questions to discuss include: Whether you meet NHS criteria for GLP-1 prescription (type 2 diabetes or obesity with complications) The evidenceor lack thereoffor GLP-1 use specifically in Hashimoto's management Potential interactions between GLP-1 medications and thyroid hormone replacement How GLP-1 therapy might affect your thyroid function monitoring schedule Alternative evidence-based approaches to managing metabolic symptoms in Hashimoto's The costs and practicalities of private prescription if NHS funding is not available Contraception requirements if you are of childbearing potential (GLP-1 medications should be avoided in pregnancy and breastfeeding) Your GP may recommend optimising your current thyroid management first , ensuring your levothyroxine dose is appropriate and that you are not over- or under-replaced