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In this study patients were followed 12 months after injection
(1) modulating antigen presentation to lymphocytes, thereby influencing cytokine production and type of response (cellular or humoral) that develops, (2) enhancing proliferation of lymphocytes, thereby increasing magnitude of response, (3) enhancing killing activity of cytotoxic T cells and NK cells, and (4) regulating apoptosis, thereby maintaining control of the immune response
We consolidate existing findings on the therapeutic potential of targeting the macrophage-ferroptosis axis, with a specific focus on oncological applications
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