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Khatri N, Sumadhura B, Kumar S, Kaundal RK, Sharma S, Datusalia AK

Fatigue can occur

Vitamin C serums can also be beneficial, but are irritating to some patients and can cause perioral dermatitis. Avoid fragrances as these often lead to allergic contact dermatitis, and also avoid the use of too many products or overcomplicating a regimen, as rashes such as perioral dermatitis commonly develop when too many irritants (e.g., retinoid, Vitamin C, AHA, salicylic acid) are used together

they translate to real-world benefits such as reduced body mass index (BMI) and improvements in conditions like obstructive sleep apnea