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A clear improvement of ataxia by 44% and 20% was observed in two patients, respectively, as measured by the ICARS score, an objective assessment that quantifies the magnitude of improvement in progressive ataxias, with a score of 5%-20% considered as substantial in providing a clinical impact

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Abnormal uterine bleeding on hormone replacement: the importance of intrauterine structural abnormalities. Obstetrics & Gynecology 86.3 (1995): 330-334