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Ultimately, personalized nutritional strategies-incorporating genetic background, trace element status, and gut microbiota composition-represent a promising direction for the precise prevention and management of AITD ( Figure 1 )

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Furthermore, ferroptosis suppression can attenuate pyroptosis by lowering the release of pro-inflammatory cytokines ( Numerous important molecular pathways are involved in the crosstalk between ferroptosis, necroptosis, and pyroptosis