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On the basis of novel data and hypothesis on the possible role of scarce glutathione (GSH) levels in the exacerbation of COVID-19 and of the GSH depleting activity of PAC, this commentary raises the question of whether PAC may be the better choice

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The 2020 structural work reported that LY3502970 behaves as a partial agonist that is biased toward G-protein activation over -arrestin recruitment