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On the contrary, the use of peptides/peptidomimetics has never been investigated in the FXS context, but it could represent a viable solution as it might result in a compensation of FMRP absence
Second, even taken at face value, an assay-specific potency ratio is not a measure of whole-organism effect: it does not mean Dihexa is millions of times more effective in a living brain, where absorption, distribution, and signaling context all differ
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Active Ingredients of FOX04-DRI (Proxofim) Anti-Aging & Longevity, Targeted Senolytic Action Peptide The active component is FOX04-DRI (FOXO4-DRI), a synthetic peptide engineered to mimic a region involved in FOXO4 binding, with modifications intended to improve cellular uptake and functional disruption of the FOXO4p53 interaction
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