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Its exclusion significantly reduced heterogeneity in the meta-analysis

While it is far more stable at room temperature than the acetate version, refrigeration is still the best practice for preserving maximum potency and integrity for the duration of your research project

This impairment of DNA synthesis affects the rapidly dividing cells of the bone marrow earlier than other cells, resulting in the production of large, immature, hemoglobin-poor red blood cells (macrocytosis), as well as effects on white blood cells, including abnormal (hypersegmented) neutrophils and reduced overall cell counts (pancytopenia)