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NT disrupts the hydrogen bonds of proteins, impairing protein function [156, 157]

Ann Surg Oncol (2015) 22(9):296571

"FDA may still take action regarding violations of any other statutory or regulatory requirements, such as to address findings that a product may be of substandard quality or otherwise unsafe," the agency noted

L-citrulline also exerted renal protective effects by reducing IL-1 and IL-12 but increasing IL-10 secretion in human proximal tubular cells (Romero et al., 2013)