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Epidemiological studies estimate that the global prevalence of overt hypothyroidism is approximately 4.6% in the United States and 5% in Europe, with even higher rates observed in iodine-deficient regions (Persani, 2012)

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[DOI] [PubMed] [Google Scholar] Neubauer C, Yamamoto HY

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The entire mixture was then stirred for 16 h at room temperature to facilitate the coupling reactions

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S.JiangE.ThomasA

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