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The EC50 values obtained fitting the ELISA values revealed that the apparent binding affinity of the PV2-PV3 fusion protein was 61.1 nM, while that of PV2-S71 + PV3-N77 was 6.1 nM, representing a 10-fold improvement in binding affinity for BsNb-ncAA compared to BsNb-fusion (Fig

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Risks and Warnings Recognised in UK Clinical Guidance UK clinical guidance including the BNF, the propranolol Summary of Product Characteristics (SmPC, Section 4.4), and Resuscitation Council UK guidelines acknowledges the interaction between beta-blockers, including propranolol, and treatments used in allergic emergencies