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Cell (2012) 148(5):85271
In the AIM-HIGH trial, in high-risk patients with cardiovascular disease, addition of prolonged-release niacin (15002000 mg/dl) to standard statin therapy did not result in additional reduction of cardiovascular events (HR = 1.02
At the beginning of the study and again at weeks 20, 40, and 60, participants ate standardized meals and were instructed to eat until they felt comfortably full, while researchers measured the number of calories they consumed
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