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Off label does not mean that a treatment option is automatically prohibited

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Most human observational and intervention evidence for the effects of these drugs has been derived from populations with type 2 diabetes mellitus, and there is a need for intervention studies for older people with, and at risk of, sarcopenia to further investigate the balance of benefit and risk in these target populations

[1] [4] Common adverse effects include gastrointestinal symptoms such as nausea, diarrhea, vomiting, constipation, and abdominal discomfort, which are typically most pronounced during dose escalation