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Antidepressants, including tricyclic antidepressants (TCAs), selective serotonin reuptake inhibitors (SSRIs) and serotonin and norepinephrine re-uptake inhibitors (SNRIs), show superior pain relief in IBS-C compared to placebo [120], with SSRIs also improving motility [121]

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As I explained in my previous post, Is There a Miracle Cure for Rotator Cuff and Other Joint Injuries?, I too have struggled with shoulder pain, and I tried everything short of surgery to alleviate the pain and get back to working out, hiking, and playing basketball and tennis